Thank you for learning about Full Spectrum Synergy with OM Extracts! Our playshop, learning experiences and literature are grounded by the research of these peer-reviewed scientific references :
Andre, Christelle M., et al. “Cannabis Sativa: The Plant of the Thousand and One Molecules.” Frontiers in Plant Science, vol. 7, 2016, doi:10.3389/fpls.2016.00019.
Izzo, Angelo A, et al. “Non-Psychotropic Plant Cannabinoids: New Therapeutic Opportunities from an Ancient Herb.” Trends in Pharmacological Sciences, vol. 30, no. 12, 2009, p. 609., doi:10.1016/j.tips.2009.10.007.
Maccallum, Caroline A., and Ethan B. Russo. “Practical Considerations in Medical Cannabis Administration and Dosing.” European Journal of Internal Medicine, vol. 49, 2018, pp. 12–19., doi:10.1016/j.ejim.2018.01.004.
McPartland, J. M., & Russo, E. B. (2001). Cannabis and cannabis extracts: Greater than the sum of their parts? Journal of Cannabis Therapeutics, 1(3–4), 103–132. http://doi.org/10. 1300/J175v01n03_08.
Romano, Luigi., Hazekamp, Arno. “Cannabis oil: chemical evaluation of an upcoming cannabis based medicine.” IACM Journal, vol. 1(1), 2013, pp. 1-11.
Russo, Ethan & Marcu, Jahan. (2017). Cannabis Pharmacology: The Usual Suspects and a Few Promising Leads. Advances in Pharmacology. . 10.1016/bs.apha.2017.03.004.
Russo, E. B. (2011). Taming THC: Potential cannabis synergy and phytocannabinoid terpenoid entourage effects. British Journal of Pharmacology, 163(7), 1344–1364. http:// doi.org/10.1111/j.1476-5381.2011.01238.x.
Russo, E. B. (2013). Cannabis strains: Do cannabis strains differ? Retrieved January 18, 2017, from http://www.cannabis-med.org/index.php?tpl¼faq&red¼faqlist&id¼278&lng¼en.
Russo, E. B. (2019). The Case for the Entourage Effect and Conventional Breeding of Clinical Cannabis: No “Strain,” No Gain. Frontiers in Plant Science”. Vol 9, Article 1969. Doi: 10.3389/fpls.2018.01969 https://www.frontiersin.org/articles/10.3389/fpls.2018.01969/full
“…the case for Cannabis synergy via the “entourage effect” is currently sufficiently strong as to suggest that one molecule is unlikely to match the therapeutic and even industrial potential of Cannabis itself as a phytochemical factory.”
Russo, E. B., & Guy, G. W. (2006). A tale of two cannabinoids: The therapeutic rationale for combining tetrahydrocannabinol and cannabidiol. Medical Hypotheses, 66(2), 234–246. http://dx.doi.org/10.1016/j.mehy.2005.08.026.
Sinclair, Justin. An introduction to cannabis and the endocannabinoid system. Australian Journal of Herbal Medicine, Vol. 28, No. 4, 2016: 107-125.
Whittle, Brian A., et al. “Prospects for New Cannabis-Based Prescription Medicines.” Journal of Cannabis Therapeutics, vol. 1, no. 3-4, 2001, pp. 183–205., doi:10.1300/j175v01n03_12.
Zgair, A., Wong, J. C., Lee, J. B., Mistry, J., Sivak, O., Wasan, K. M., Hennig, I. M., Barrett, D. A., Constantinescu, C. S., Fischer, P. M., … Gershkovich, P. (2016). Dietary fats and pharmaceutical lipid excipients increase systemic exposure to orally administered cannabis and cannabis-based medicines. American journal of translational research, 8(8), 3448-59. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5009397/
Zgair, A., et al. (2017). Oral administration of cannabis with lipids leads to high levels of cannabinoids in the intestinal lymphatic system and prominent immunomodulation. Scientific Reports, 7, Article 14542. https://www.nature.com/articles/s41598-017-15026-z/